I checked out the power requirements and here is what I found. First, using my Toshiba XS700 240gb as the boot drive plugged directly into the computer:
Second, the Samsung T7 500 gb booting directly into the computer:
Third, the Samsung T7 500 gb booting from the Insignia 3.0 USB hub:
So, no difference between booting the T7 directly from the computer vs hub.
These results are from a 2012 Mac Mini i7 QuadCore 2.3 GHz.