Hi Diane. Yes, looking at the image you posted, the artifacts around the wheel wells and other locations are caused by Digital ICE with Kodachrome.
If you end up using the Kodachrome-iSRD software David C. mentions let us know how it works out.
If using the Epson software you can either scan your Kodachrome slides without Digital ICE, or for the ones that are particularly dirty (even after careful cleaning), you can do two scans: one with Digital ICE, and one without. Then, using Pixelmator or Photoshop or similar, put the Digital ICE version on top and cut out the artifacts to reveal the non-DI version underneath. (Or put the non-DI version on top and cut out the areas that don’t have much visible dirt). Or live with the dirt, sometimes it’s aesthetically pleasing because it adds some old school charm to the shots. 
The 64-bit Epson software no longer includes Digital ICE, unless they reinstated it since I was doing the slide scanning several years ago. I found the 32-bit Epson software’s Digital ICE was much better quality than the VueScan and Silverfast infrared scanning dust removal options, maybe because it didn’t offer parameters so they were forced to tune it to work well from the get-go. I used a virtual machine with Mojave so that I could scan with the old 32-bit software. A Windows 10 virtual machine will accomplish the same thing.
I wrote up a slide and photo scanning guide for the Epson software–let me know if you need it and I’ll see if I can dig it up.