I use Filemaker despite its limitations such as a lack of a high-level programming language. I did look at Libre Office which (unlike MS Office) includes a database module for managing MySQL data. It may be worth a look (and it is free).
I can beat “4D” from 1998 - I still use the 1985 DOS-based Open Access 4 for complex database operations and programming. It runs happily on a Mac in DOSBox emulator (which is intended for games). Of course it does not have a graphics user interface and these days can only exchange data via text files but, for me, it is a bit like keeping a vintage car (Rolls Royce?) going.
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